Lindamic
Clindamycin is Very Effective Against Skin and soft Tissue Infections
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CLINDAMYCIN
CLINDAMYCIN 600 MG / 300 MG for IV / IM Inj
CLINDAMYCIN 150 mg / 300 mg Capsules
Lindamic contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Each ml contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each ml. Clindamycin is a semisynthetic antibiotic produced by a 7(S)chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin.
PHARMACOLOGY
IV/IM Injection: Biologically inactive clindamycin phosphate is rapidly converted to active clindamycin. By the end of short-term intravenous infusion, peak serum levels of active clindamycin are reached. Biologically inactive clindamycin phosphate disappears rapidly from the serum; the average elimination half-life is 6 minutes; however, the serum elimination half-life of active clindamycin is about 3 hours in adults and 2½ hours in pediatric patients.